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The US National Academy of Medicine (NAM)’s first global grand challenge is dedicated to healthy longevity. We summarize the NAM’s Global Roadmap for Healthy Longevity, highlighting evidence that societies can benefit from untapped human, social and economic capital through investments throughout the life course.
In the age of rapid technological advance there are myths about older adults’ difficulties in using technology. Here I will debunk two common myths: first, the idea that age-related functional decline is entirely responsible; and second, the notion that everyone will be technologically adept once today’s older adults are gone.
The successful adoption and use of technology products and services for older adults remain limited. Although technological developments promise improved quality of life for older adults, ageism and access gaps impede their use. Implications and recommendations the design and distribution of new technologies for aging in place are discussed.
Currently, there are no evidence-based interventions to prevent and respond to abuse of older people. We propose to create, within the Decade of Healthy Ageing 2021–2030, an intervention accelerator to speed up the development of effective interventions for abuse of older people in community and institutional settings within low-, middle- and high-income countries.
The aging research field has largely focused on reversing aging-related changes in the body. However, emerging evidence about the gut microbiome indicates that it may not be optimal to just turn back the clock. Here, we advocate for a more tailored and function-focused approach promoting health across the lifespan.
Aging can be conceptualized as the stochastic accumulation of damage and loss of resilience leading to organism demise. Resilience mechanisms that repair, recycle or replace damaged molecules and organelles are energy-demanding, therefore energy availability is essential to healthy aging. We propose that changes in mitochondrial and energy status regulate RNA splicing and that splicing is a resilience strategy that preserves energetic homeostasis with aging.
Plasma biomarkers pertaining to the underlying pathophysiology of Alzheimer’s disease have recently become available (for example, amyloid beta and phosphorylated tau). The utility of these markers poses a question for clinicians (now and in the future): are plasma biomarkers for Alzheimer’s disease are ready for clinical use at this time?
