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This cover image shows immunofluorescence staining of tight junction protein Claudin-1 in a whole mount cornea from ST2 (IL-33 receptor)-/- mice with experimental allergic conjunctivitis induced by topical eye challenge after sensitization with short ragweed pollen. The image demonstrates that ST2-defi cient mice lack the corneal barrier disruption seen in wild type mice following pollen challenge. Image courtesy of De-Quan Li, Baylor College of Medicine. For further information please see article in this this issue, pages 919–930.