Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Perinatal/Neonatal Case Presentation
  • Published:

Perinatal/Neonatal Case Presentation

Subgaleal hemorrhage in a neonate with factor X deficiency following a non-traumatic cesarean section

Journal of Perinatology volume 32, pages 304–305 (2012)Cite this article

Subjects

Abstract

This case report describes a term infant born by a non-traumatic, non-instrumented cesarean section that presented with respiratory failure and severe metabolic acidosis secondary to subgaleal hemorrhage (SGH). Further evaluation revealed a functional factor X deficiency that was initially treated with fresh frozen plasma infusions. This report is significant for the occurrence of a SGH in a non-traumatic delivery and emphasizes the importance of obtaining a coagulopathy evaluation in patients with similar presentations. In addition, this case suggests that the mechanism of injury that causes SGH may occur more frequently than previously thought, but does not become clinically significant in patients without an underlying coagulopathy.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1

Similar content being viewed by others

References

  1. Davis DJ . Neonatal subgaleal hemorrhage: diagnosis and management. CMAJ 2001; 164 (10): 1452–1453.

    CAS  PubMed  PubMed Central  Google Scholar 

  2. Chang HY, Peng CC, Kao HA, Hsu CH, Hung HY, Chang JH . Neonatal subgaleal hemorrhage: clinical presentation, treatment, and predictors of poor prognosis. Pediatr Int 2007; 49 (6): 903–907.

    Article  Google Scholar 

  3. Doumouchtsis SK, Arulkumaran S . Head trauma after instrumental births. Clin Perinatol 2008; 35 (1): 69–83, viii.

    Article  Google Scholar 

  4. Gebremariam A . Subgaleal haemorrhage: risk factors and neurological and developmental outcome in survivors. Ann Trop Paediatr 1999; 19 (1): 45–50.

    Article  CAS  Google Scholar 

  5. Christensen RD, Baer VL, Henry E . Neonatal subgaleal hemorrhage in a multihospital healthcare system: prevalence, associations, and outcomes. e-J Neonatol Res 2011; 1 (1): 1–8.

    Google Scholar 

  6. Plauche WC . Subgaleal hematoma. A complication of instrumental delivery. JAMA 1980; 244 (14): 1597–1598.

    Article  CAS  Google Scholar 

  7. Kulkarni R, Lusher J . Perinatal management of newborns with haemophilia. Br J Haematol 2001; 112 (2): 264–274.

    Article  CAS  Google Scholar 

  8. Kulkarni R, Lusher JM . Intracranial and extracranial hemorrhages in newborns with hemophilia: a review of the literature. J Pediatr Hematol Oncol 1999; 21 (4): 289–295.

    Article  CAS  Google Scholar 

  9. Rohyans JA, Miser AW, Miser JS . Subgaleal hemorrhage in infants with hemophilia: report of two cases and review of the literature. Pediatrics 1982; 70 (2): 306–307.

    CAS  PubMed  Google Scholar 

  10. Menegatti M, Peyvandi F . Factor X deficiency. Semin Thromb Hemost 2009; 35 (4): 407–415.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. The Perinatal Institute, Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA

    E A Wetzel & P S Kingma

Authors
  1. E A Wetzel
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P S Kingma
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to P S Kingma.

Ethics declarations

Competing interests

The authors declare no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wetzel, E., Kingma, P. Subgaleal hemorrhage in a neonate with factor X deficiency following a non-traumatic cesarean section. J Perinatol 32, 304–305 (2012). https://doi.org/10.1038/jp.2011.122

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/jp.2011.122

Keywords

This article is cited by

Search

Advanced search

Quick links