Abstract
An uncommon clinical entity mimicking necrotizing enterocolitis (NEC) is allergic enterocolitis secondary to cow's milk protein allergy. Although milk protein allergy is the most common food allergy among infants and young children, the incidence and prevalence of this disease entity presenting as enterocolitis in neonates is not well documented. We report this case of milk protein-associated allergic enterocolitis to highlight the unusual recurrent presentation as NEC, (with recurrent pneumatosis, bloody stools) managed successfully with modification of milk formula.
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References
Maloney J, Nowak-Wegrzyn A . Educational clinical case series for pediatric allergy and immunology: allergic proctocolitis, food protein-induced enterocolitis syndrome and allergic eosinophilic gastroenteritis with protein-losing gastroenteropathy as manifestations of non-IgE-mediated cow's milk allergy. Pediatr Allergy Immunol 2007; 18: 360–367.
Gordon PV, Swanson JR, Attridge JT, Clark R . Emerging trends in acquired neonatal intestinal disease: is it time to abandon Bell's criteria? J Perinatol 2007; 27: 661–671.
Wilson NW, Self TW, Hamburger RN . Severe cow's milk induced colitis in an exclusively breast-fed neonate. Case report and clinical review of cow's milk allergy. Clin Pediatr (Phila) 1990; 29: 77–80.
Faber MR, Rieu P, Semmekrot BA, Van Krieken JH, Tolboom JJ, Draaisma JM . Allergic colitis presenting within the first hours of premature life. Acta Paediatrica 2005; 94: 1514–1515.
Fell JM . Neonatal inflammatory intestinal diseases: necrotising enterocolitis and allergic colitis. Early Hum Dev 2005; 81: 117–122.
Bahna SL . Cow's milk allergy versus cow milk intolerance. Ann Allergy Asthma Immunol 2002; 89: 56–60.
Masumoto K, Takahashi Y, Nakatsuji T, Arima T, Kukita J . Radiological findings in two patients with cow's milk allergic enterocolitis. Asian J Surg 2004; 27: 238–240.
Wilson NW, Self TW, Hamburger RN . Severe cow's milk induced colitis in an exclusively breast-fed neonate. Case report and clinical review of cow's milk allergy. Clin Pediatr (Phila) 1990; 29: 77–80.
Lake AM, Whitington PF, Hamilton SR . Dietary protein-induced colitis in breast-fed infants. J Pediatr 1982; 101: 906–910.
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Srinivasan, P., Brandler, M., D'Souza, A. et al. Allergic enterocolitis presenting as recurrent necrotizing enterocolitis in preterm neonates. J Perinatol 30, 431–433 (2010). https://doi.org/10.1038/jp.2009.153
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DOI: https://doi.org/10.1038/jp.2009.153
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