Manipulation of stem cells is an important therapeutic goal that has proven difficult to achieve. A recent report describes a novel in vivo small-molecule screen and identifies a modulator of mammalian neurogenesis that partially reverses age-related declines in cognition.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Ding, S. & Schultz, P.G. Nat. Biotechnol. 22, 833–840 (2004).
Pieper, A.A. et al. Cell 142, 39–51 (2010).
Zhao, C., Deng, W. & Gage, F.H. Cell 132, 645–660 (2008).
Deng, W., Aimone, J.B. & Gage, F.H. Nat. Rev. Neurosci. 11, 339–350 (2010).
Ding, S. et al. Proc. Natl. Acad. Sci. USA 100, 7632–7637 (2003).
Saxe, J.P. et al. Chem. Biol. 14, 1019–1030 (2007).
Pieper, A.A. et al. Proc. Natl. Acad. Sci. USA 102, 14052–14057 (2005).
Min, J. et al. Nat. Chem. Biol. 3, 55–59 (2007).
North, T.E. et al. Nature 447, 1007–1011 (2007).
Miller, G. Science 327, 1309 (2010).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Saxe, J. Your brain on drugs. Nat Chem Biol 6, 639–640 (2010). https://doi.org/10.1038/nchembio.427
Issue Date:
DOI: https://doi.org/10.1038/nchembio.427
