The microRNA miR-9 is induced by Myc in breast cancer cells where it targets the major epithelial adherens junction protein, E-cadherin. This primes the cancer cells for epithelial–mesenchymal transition (EMT) and also stimulates angiogenesis in tumours.
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Khew-Goodall, Y., Goodall, G. Myc-modulated miR-9 makes more metastases. Nat Cell Biol 12, 209–211 (2010). https://doi.org/10.1038/ncb0310-209
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DOI: https://doi.org/10.1038/ncb0310-209
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