Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Cancer

An acidic link

Nature volume 499, pages 37–38 (2013)Cite this article

Subjects

Obese people are at higher risk of multiple types of cancer, but why? One explanation could be that obesity enhances the production of pro-inflammatory, and carcinogenic, bile acids by gut microorganisms. See Letter p.97

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: How obesity increases cancer risk.

Notes

  1. *This article and the paper under discussion4 were published online on 26 June 2013.

References

  1. Park, E. J. et al. Cell 140, 197–208 (2010).

    Article  CAS  Google Scholar 

  2. Greenblum, S., Turnbaugh, P. J. & Borenstein, E. Proc. Natl Acad. Sci. USA 109, 594–599 (2012).

    Article  CAS  ADS  Google Scholar 

  3. Fei, N. & Zhao, L. ISME J. 7, 880–884 (2013).

    Article  CAS  Google Scholar 

  4. Yoshimoto, S. et al. Nature 499, 97–101 (2013).

    Article  CAS  ADS  Google Scholar 

  5. Coppe, J. P. et al. PLoS Biol. 6, 2853–2868 (2008).

    Article  CAS  Google Scholar 

  6. Turnbaugh, P. J., Backhed, F., Fulton, L. & Gordon, J. I. Cell Host Microbe 3, 213–223 (2008).

    Article  CAS  Google Scholar 

  7. Nagengast, N. M. et al. Eur. J. Cancer 31, 1067–1070 (1995).

    Article  Google Scholar 

  8. Devkota, S. et al. Nature 487, 104–108 (2012).

    Article  CAS  ADS  Google Scholar 

  9. Martens, E. C. et al. PLoS Biol. 9, e1001221 (2011).

    Article  CAS  Google Scholar 

  10. Sayin, S. I. et al. Cell Metab. 17, 225–235 (2013).

    Article  CAS  MathSciNet  Google Scholar 

  11. Ahmad, N. N., Pfalzer, A. & Kaplan, L. M. Int. J. Obes. http://dx.doi.org/10.1038/ijo.2013.38 (2013).

  12. Swann, J. R. et al. Proc. Natl Acad. Sci. USA 108 (Suppl. 1), 4523–4530 (2011).

    Article  CAS  ADS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Suzanne Devkota is at the Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts 02215, USA.,

    Suzanne Devkota

  2. Peter. J. Turnbaugh is at the FAS Center for Systems Biology, Harvard University, Cambridge, Massachusetts 02138, USA.,

    Peter. J. Turnbaugh

Authors
  1. Suzanne Devkota
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Peter. J. Turnbaugh
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Peter. J. Turnbaugh.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Devkota, S., Turnbaugh, P. An acidic link. Nature 499, 37–38 (2013). https://doi.org/10.1038/nature12404

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature12404

Search

Advanced search

Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer