In vitro fertilization (IVF) and aneuploidy
- Submission status
- Open
- Submission deadline
Fetal aneuploidy can lead to developmental abnormalities as well as implantation failure after in vitro fertilization. Preimplantation genetic testing for aneuploidy (PGT-A) is designed to minimize these risks.
PGT-A encompasses a range of methods, including comparative genomic hybridization, single nucleotide polymorphism array, quantitative PCR, and next-generation sequencing, using either a blastomere or trophectoderm cells from the blastocyst. These methods vary in their ability to detect partial aneuploidy (where one chromosomal portion is duplicated or absent in all cells), mosaicism, and partial mosaicism (where one cell line is euploid and the other is partial aneuploid). While advances in biopsy, screening, and embryo culture techniques have improved the efficacy and accessibility of PGT-A, there remains some debate over the evidence supporting its widespread use.
This Collection will highlight original research on all aspects of IVF and aneuploidy, including current approaches in preimplantation genetic testing and the clinical implications of preimplantation aneuploidy and mosaicism.
Editors
-
Yasushi Hirota, MD, PhD
Department of Obstetrics and Gynecology, Graduate School of Medicine, University of Tokyo, Japan
-
Michał Kunicki, MD, PhD
Medical University of Warsaw, Poland INVICTA Fertility Clinic, Warsaw, Poland
Submitting a paper for consideration
To submit your manuscript for consideration at Scientific Reports as part of this Collection, please follow the steps detailed on this page. On the first page of our online submission system, under “I’m submitting:” select the option “any other article type”. Once logged in you can submit your manuscript to a Collection by selecting “Guest Edited Collection”, under the “Choose the appropriate manuscript type” message, and clicking “Continue”. Then when filling out the manuscript information, select the "In vitro fertilization (IVF) and aneuploidy" Collection from the alphabetical list on the “Springer Nature Subject Category” tab. Authors should express their interest in the Collection in their cover letter.
Accepted papers are published on a rolling basis as soon as they are ready.
In addition to papers on In vitro fertilization (IVF) and aneuploidy, Scientific Reports welcomes all original research in the field of Biological sciences. To browse our latest articles in Biological sciences click here.
