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ATHEROSCLEROSIS

SNCs meet SMCs in the atherosclerotic plaque

Nature Aging volume 1, pages 631–633 (2021)Cite this article

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Cellular senescence and smooth muscle cells are key features of the atherosclerotic plaque; however, how senescent cells regulate smooth muscle cells is largely unknown. Herein, a new study in Nature Aging illuminates this interplay, providing insights into plaque dynamics and stability with potentially profound implications for heart attack and stroke.

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Fig. 1: SNCs regulate the SMC lineage in the atherosclerotic plaque.

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Authors and Affiliations

  1. Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University, New Haven, CT, USA

    Inamul Kabir & Daniel M. Greif

  2. Department of Genetics, Yale University, New Haven, CT, USA

    Inamul Kabir & Daniel M. Greif

Authors
  1. Inamul Kabir
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  2. Daniel M. Greif
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Correspondence to Daniel M. Greif.

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The authors declare no competing interests.

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Kabir, I., Greif, D.M. SNCs meet SMCs in the atherosclerotic plaque. Nat Aging 1, 631–633 (2021). https://doi.org/10.1038/s43587-021-00096-6

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