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Thyroid metabolism

The thyroid gland under Notch control

A study in Nature Metabolism shows that the thyroid gland contains two subtypes of thyrocytes (the cells that produce thyroid hormones) and reveals a role for Notch signalling in regulating thyrocyte homeostasis and activity, as reduced Notch activity results in hypothyroidism.

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Fig. 1: A role for Notch signalling in the thyroid.

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Acknowledgements

The research in the author’s laboratory is financed by project grants from the Swedish Research Council (2019:00285), the Swedish Cancer Society (4-370/2019), the Swedish Brain Foundation (F2020-0246) and the Erling-Persson Family Foundation. The funders had no role in decision to publish or prepare this work.

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Correspondence to Urban Lendahl.

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Lendahl, U. The thyroid gland under Notch control. Nat Metab 5, 2037–2038 (2023). https://doi.org/10.1038/s42255-023-00911-x

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