Core body temperature and metabolic rate have both been proposed to regulate longevity, but their relative contribution had not been determined. Zhao et al. separated the effects of these two parameters in mice and hamsters, revealing that core body temperature is a more important determinant of longevity than metabolic rate.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Cold temperature extends longevity and prevents disease-related protein aggregation through PA28γ-induced proteasomes
Nature Aging Open Access 03 April 2023
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 digital issues and online access to articles
$119.00 per year
only $9.92 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Pearl, R. The Rate of Living. (Univ. London Press, 1928).
Rubner, M. Das Problem det Lebensdaur und Seiner Beziehunger zum Wachstum und Ernarnhung (Oldenberg, 1908).
Loeb, J. & Northrop, J. H. Proc. Natl Acad. Sci. USA 2, 456–457 (1916).
Conti, B. et al. Science 314, 825–828 (2006).
Roth, G. S. et al. Science 297, 811 (2002).
Waalen, J. & Buxbaum, J. N. J. Gerontol. A Biol. Sci. Med. Sci. 66A, 487–492 (2011).
Protsiv, M., Ley, C., Lankester, J., Hastie, T. & Parsonnet, J. eLife 9, e49555 (2020).
Zhao, Z. et al. Nat. Metabol., https://doi.org/10.1038/10.1038/s42255-022-00545-5 (2022).
Lane, M. A. et al. Proc. Natl Acad. Sci. USA 93, 4159–4164 (1996).
Soare, A., Cangemi, R., Omodei, D., Holloszy, J. O. & Fontana, L. Aging 3, 374–379 (2011).
Cintron-Colon, R. et al. Proc. Natl Acad. Sci. USA 114, 9731–9736 (2017).
Koizumi, A. et al. Mech. Ageing Dev. 92, 67–82 (1996).
Carvalho, G. B. et al. Proc. Natl Acad. Sci. USA 114, 9737–9742 (2017).
Xiao, R. et al. Cell 152, 806–817 (2013).
Guijas, C. et al. Sci. Signal. 13, eabb2490 (2020).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing interests.
Rights and permissions
About this article
Cite this article
Conti, B. Hot news about temperature and lifespan. Nat Metab 4, 303–304 (2022). https://doi.org/10.1038/s42255-022-00542-8
Published:
Issue Date:
DOI: https://doi.org/10.1038/s42255-022-00542-8