Correction to: Nature Neuroscience https://doi.org/10.1038/s41593-020-00765-6, published online 11 January 2021.

In the version of this article initially published, the second sentence of the Methods section “Comparison of mutational signatures between earlier and later mutations” should have read, “To avoid over-fitting, we extracted the two most common clock-like signatures (signature S1 and signature S5), as well as a reactive oxygen species signature (signature S18) from the PCAWG signatures, and deconstructed mutational signatures for the mosaic mutations using the R package deconstructSigs67.” The error has been corrected in the PDF and HTML versions of this article.