A new study reveals that maternal immune activation promotes sex-biased activation of the integrated stress response in the developing mouse brain and that this mechanistically contributes to the onset of autism-related behaviors uniquely in male offspring.
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Zengeler, K.E., Lukens, J.R. Inflammation stresses out brain development. Nat Neurosci 24, 155–157 (2021). https://doi.org/10.1038/s41593-020-00775-4
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DOI: https://doi.org/10.1038/s41593-020-00775-4