Molecular neuroscience

Definition

Molecular neuroscience is a branch of neuroscience that examines the biology of the nervous system with molecular biology, molecular genetics, protein chemistry and related methodologies.

Featured

Latest Research and Reviews

News and Comment

  • News and Views |

    Extracellular vesicles (EVs) are a class of secreted membrane particles capable of transferring biological molecules between cells. Metabolomics measurements indicate that isolated EVs also have autonomous metabolic enzyme activities, including the unexpected identification of endogenous human asparaginase activity.

    • Lucas B Sullivan
  • News and Views |

    A Cre-dependent capsid selection method, CREATE, was used to produce adeno-associated viral vectors that allow gene delivery to the entire central and peripheral nervous systems, with multicolor labeling of single cells.

    • Keisuke Yonehara
    •  & Botond Roska
    Nature Neuroscience 20, 1041–1042
  • News and Views |

    In early-stage developing neurons, the cAMP–PKA (protein kinase A) signaling pathway is strongly inhibited. This negative control is later removed, unleashing cAMP–PKA signaling, particularly in distal axonal parts, thus allowing for axonal growth.

    • Pierre Vincent
    •  & Liliana R Castro