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Cell biology

Line-scanning speeds up Brillouin microscopy

Nature Methods volume 20, pages 643–644 (2023)Cite this article

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Two new Brillouin microscopes leverage line-scanning to overcome previous limitations of the technique, enabling fast imaging, with low phototoxicity, of mechanical properties in living embryos of model organisms and tumor spheroids.

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Fig. 1: Principle of line-scanning Brillouin microscopy.

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Acknowledgements

N.K. was supported by a Leverhulme Trust project grant (RPG-2020-068) awarded to Y.M. G.P. was supported by an EMBO Long-Term Fellowship (ALTF 786-2020). Y.M. was funded by an MRC award MR/W027437/1, a Lister Institute Research Prize and the EMBO Young Investigator Programme.

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Author notes

  1. These authors contributed equally: Nargess Khalilgharibi, Giulia Paci.

Authors and Affiliations

  1. Laboratory for Molecular Cell Biology, University College London, London, UK

    Nargess Khalilgharibi, Giulia Paci & Yanlan Mao

  2. Institute for the Physics of Living Systems, University College London, London, UK

    Nargess Khalilgharibi, Giulia Paci & Yanlan Mao

Authors
  1. Nargess Khalilgharibi
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  2. Giulia Paci
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  3. Yanlan Mao
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Correspondence to Yanlan Mao.

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Khalilgharibi, N., Paci, G. & Mao, Y. Line-scanning speeds up Brillouin microscopy. Nat Methods 20, 643–644 (2023). https://doi.org/10.1038/s41592-023-01843-w

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