Clinical disease trajectories that describe neuropsychiatric symptoms were identified using natural language processing for 3,042 brain donors diagnosed with various neurodegenerative disorders. Trajectories revealed distinct temporal patterns that result in the identification of new clinical subtypes, and a subset of misdiagnosed donors.
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This is a summary of: Mekkes, N. J. et al. Identification of clinical disease trajectories in neurodegenerative disorders with natural language processing. Nat. Med. https://doi.org/10.1038/s41591-024-02843-9 (2024).
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Revealing clinical heterogeneity in a large brain bank cohort. Nat Med 30, 956–957 (2024). https://doi.org/10.1038/s41591-024-02871-5
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DOI: https://doi.org/10.1038/s41591-024-02871-5
