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Innate immunity

Thanks for the NK cell memories

Nature Immunology volume 23, pages 1512–1514 (2022)Cite this article

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Clonal expansion and immunological memory of lymphocytes provide protective immunity against repeated pathogen exposure in mammals. New technologies are enabling the investigation of these intricate processes, focusing on human natural killer cells during human cytomegalovirus infection.

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Fig. 1: Clonal NK cell expansion and generation of clonal memory populations.

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Acknowledgements

S.G. is supported by a fellowship from the Cancer Research Institute. J.C.S. is supported by the Ludwig Center for Cancer Immunotherapy, the American Cancer Society, the Burroughs Wellcome Fund and the NIH (AI100874, AI130043 and AI155558).

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Authors and Affiliations

  1. Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Simon Grassmann & Joseph C. Sun

  2. Immunology and Microbial Pathogenesis Program, Graduate School of Medical Sciences, Weill Cornell Medical College, New York, NY, USA

    Joseph C. Sun

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  1. Simon Grassmann
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  2. Joseph C. Sun
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Correspondence to Joseph C. Sun.

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Grassmann, S., Sun, J.C. Thanks for the NK cell memories. Nat Immunol 23, 1512–1514 (2022). https://doi.org/10.1038/s41590-022-01336-6

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