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IMMUNOLOGY

Organ immune responses — don’t forget the structural cells

Nature Reviews Nephrology volume 16, pages 570–571 (2020)Cite this article

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The generation of local immune responses in organs requires a coordinated effort, not just from immune cells, but also from ‘structural’ cells such as epithelial cells, endothelial cells and fibroblasts. New insights gained from profiling these cells across organs in the mouse emphasizes the important contribution of this structural cell network to organ immunity.

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Fig. 1: The immune potential of structural cells.

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Authors and Affiliations

  1. Molecular Immunity Unit, University of Cambridge Department of Medicine, Cambridge, UK

    Zewen Kelvin Tuong & Menna R. Clatworthy

  2. Cellular Genetics, Wellcome Sanger Institute, Hinxton, UK

    Zewen Kelvin Tuong & Menna R. Clatworthy

Authors
  1. Zewen Kelvin Tuong
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  2. Menna R. Clatworthy
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Correspondence to Menna R. Clatworthy.

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The authors declare no competing interests.

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Tuong, Z.K., Clatworthy, M.R. Organ immune responses — don’t forget the structural cells. Nat Rev Nephrol 16, 570–571 (2020). https://doi.org/10.1038/s41581-020-00334-x

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