A new study provides evidence that platelets exert potent inflammatory effects and play a central part in the progression from simple steatosis to nonalcoholic steatohepatitis. The results from this and other studies raise important questions regarding the role of platelets in the development of hepatocellular carcinoma in individuals with fatty liver disease.
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Diggs, L.P., Greten, T.F. The effects of platelet accumulation in fatty liver disease. Nat Rev Gastroenterol Hepatol 16, 393–394 (2019). https://doi.org/10.1038/s41575-019-0160-8
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DOI: https://doi.org/10.1038/s41575-019-0160-8