Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Clinical Outlook
  • Published:

Long-term outcomes and device failure after TAVI

Nature Reviews Cardiology volume 21, pages 3–4 (2024)Cite this article

Subjects

Transcatheter aortic valve implantation (TAVI) has become an important treatment option for aortic stenosis, even among younger patients, with similar rates of efficacy as compared with surgical valve replacement. However, complications including device failure persist; these can be addressed by surgical explantation and repeat TAVI. Ongoing research emphasizes the long-term potential of TAVI as an alternative to surgical intervention for aortic stenosis.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Rates of TAVI device failure and clinical end points in long-term studies.

References

  1. Otto, C. M. et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation 143, e72–e227 (2021).

    PubMed  Google Scholar 

  2. Sharma, T., Krishnan, A. M., Lahoud, R., Polomsky, M. & Dauerman, H. L. National trends in TAVR and SAVR for patients with severe isolated aortic stenosis. J. Am. Coll. Cardiol. 80, 2054–2056 (2022).

    Article  PubMed  Google Scholar 

  3. Salaun, E. et al. Rate, timing, correlates, and outcomes of hemodynamic valve deterioration after bioprosthetic surgical aortic valve replacement. Circulation 138, 971–985 (2018).

    Article  PubMed  Google Scholar 

  4. Capodanno, D. et al. Standardized definitions of structural deterioration and valve failure in assessing long-term durability of transcatheter and surgical aortic bioprosthetic valves: a consensus statement from the European Association of Percutaneous Cardiovascular Interventions (EAPCI) endorsed by the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur. Heart J. 38, 3382–3390 (2017).

    Article  PubMed  Google Scholar 

  5. Lerman, T. T. et al. Comparison of middle-term valve durability between transcatheter aortic valve implantation and surgical aortic valve replacement: an updated systematic review and meta-analysis of RCTs. Front. Cardiovasc. Med. 10, 1242608 (2023).

    Article  PubMed  PubMed Central  Google Scholar 

  6. Arjunon, S., Rathan, S., Jo, H. & Yoganathan, A. P. Aortic valve: mechanical environment and mechanobiology. Ann. Biomed. Eng. 41, 1331–1346 (2013).

    Article  PubMed  PubMed Central  Google Scholar 

  7. Barbanti, M. & Tamburino, C. Late degeneration of transcatheter aortic valves: pathogenesis and management. EuroIntervention 12, Y33–Y36 (2016).

    Article  PubMed  Google Scholar 

  8. Jorgensen, J. et al. The Nordic Aortic Valve Intervention (NOTION) trial, 10 years follow-up. European Society of Cardiology Congress, https://esc365.escardio.org/presentation/272247?resource=slide (2023).

  9. Tang, G. H. L. et al. Explant vs redo-TAVR after transcatheter valve failure: mid-term outcomes from the EXPLANTORREDO-TAVR international registry. JACC Cardiovasc. Interv. 16, 927–941 (2023).

    Article  PubMed  Google Scholar 

  10. Makkar, R. R. et al. Outcomes of repeat transcatheter aortic valve replacement with balloon-expandable valves: a registry study. Lancet https://doi.org/10.1016/S0140-6736(23)01636-7 (2023).

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Università degli Studi di Enna Kore, Enna, Italy

    Marco Barbanti

  2. Centre for Heart Valve Innovation, St. Paul’s Hospital, University of British Columbia, Vancouver, British Columbia, Canada

    John G. Webb

Authors
  1. Marco Barbanti
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. John G. Webb
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Marco Barbanti.

Ethics declarations

Competing interests

M.B. is a consultant for Boston Scientific, Edwards Lifesciences and Medtronic. J.G.W. is a consultant for Edwards Lifesciences and has received research funding from Boston Scientific, Edwards Lifesciences and Medtronic.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Barbanti, M., Webb, J.G. Long-term outcomes and device failure after TAVI. Nat Rev Cardiol 21, 3–4 (2024). https://doi.org/10.1038/s41569-023-00954-3

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41569-023-00954-3

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing