Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Heart failure

Implementing an earlier and more intensive follow-up in acute heart failure: the STRONG-HF and COACH trials

Nature Reviews Cardiology volume 20, pages 213–214 (2023)Cite this article

Subjects

The STRONG-HF and COACH trials have shown a reduction in morbidity and mortality in patients with acute decompensated heart failure, for whom therapeutical options are currently limited, using two different approaches that have in common the aim of more effective treatment optimization through a better transition phase from in-hospital to outpatient care.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Savarese, G. et al. Heart failure drug treatment-inertia, titration, and discontinuation: a multinational observational study (EVOLUTION HF). JACC Heart Fail. 11, 1–14 (2023).

    Article  PubMed  Google Scholar 

  2. McDonagh, T. A. et al. 2021 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur. Heart J. 42, 3599–3726 (2021).

    Article  CAS  PubMed  Google Scholar 

  3. Heidenreich, P. A. et al. 2022 AHA/ACC/HFSA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. J. Am. Coll. Cardiol. 79, 1757–1780 (2022).

    Article  PubMed  Google Scholar 

  4. Mebazaa, A. et al. Safety, tolerability and efficacy of up-titration of guideline-directed medical therapies for acute heart failure (STRONG-HF): a multinational, open-label, randomised, trial. Lancet 400, 1938–1952 (2022).

    Article  CAS  PubMed  Google Scholar 

  5. Stolfo, D. et al. Use of evidence-based therapy in heart failure with reduced ejection fraction across age strata. Eur. J. Heart Fail. 24, 1047–1062 (2022).

    Article  CAS  PubMed  Google Scholar 

  6. Rosano, G. M. C. et al. Patient profiling in heart failure for tailoring medical therapy. A consensus document of the Heart Failure Association of the European Society of Cardiology. Eur. J. Heart Fail. 23, 872–881 (2021).

    Article  PubMed  Google Scholar 

  7. Janse, R. J. et al. Use of guideline-recommended medical therapy in patients with heart failure and chronic kidney disease: from physician’s prescriptions to patient’s dispensations, medication adherence and persistence. Eur. J. Heart Fail. 24, 2185–2195 (2022).

    Article  PubMed  Google Scholar 

  8. Lee, D. S. et al. Trial of an intervention to improve acute heart failure outcomes. N. Engl. J. Med. 388, 22–32 (2023).

    Article  PubMed  Google Scholar 

  9. Lindberg, F. et al. Patient profile and outcomes associated with follow-up in specialty vs. primary care in heart failure. ESC Heart Fail. 9, 822–833 (2022).

    Article  PubMed  PubMed Central  Google Scholar 

  10. Savarese, G., Lund, L. H., Dahlström, U. & Strömberg, A. Nurse-led heart failure clinics are associated with reduced mortality but not heart failure hospitalization. J. Am. Heart Assoc. 8, e011737 (2019).

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Centre for Clinical and Basic Research, IRCCS San Raffaele, Rome, Italy

    Giuseppe M. C. Rosano

  2. Division of Cardiology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden

    Gianluigi Savarese

Authors
  1. Giuseppe M. C. Rosano
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Gianluigi Savarese
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Giuseppe M. C. Rosano.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Rosano, G.M.C., Savarese, G. Implementing an earlier and more intensive follow-up in acute heart failure: the STRONG-HF and COACH trials. Nat Rev Cardiol 20, 213–214 (2023). https://doi.org/10.1038/s41569-023-00841-x

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41569-023-00841-x

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing