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Does steroid increase LPS-induced sickness behaviors?

Neuropsychopharmacology (2024)Cite this article

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Dear Editor,

With respect to Martz’s inspiring article [1] we would like to point out a few results of Martz et al. that we found incomprehensible.

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References

  1. Martz J, Shelton MA, Geist L, Seney ML, Kentner AC. Sex differences in offspring risk and resilience following 11β-hydroxylase antagonism in a rodent model of maternal immune activation. Neuropsychopharmacol. 2023. https://doi.org/10.1038/s41386-023-01771-5.

  2. Liang H, Song H, Zhai R, Song G, Li H, Ding X, et al. Corticosteroids for treating sepsis in adult patients: a systematic review and meta-analysis. Front Immunol. 2021;12:709155.

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  3. Fang F, Zhang Y, Tang J, Lunsford LD, Li T, Tang R, et al. Association of corticosteroid treatment with outcomes in adult patients with sepsis: a systematic review and meta-analysis. JAMA Intern Med. 2019;179:213–23.

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  4. Tsao CM, Ho ST, Chen A, Wang JJ, Li CY, Tsai SK, et al. Low-dose dexamethasone ameliorates circulatory failure and renal dysfunction in conscious rats with endotoxemia. Shock. 2004;21:484–91.

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Author information

Authors and Affiliations

  1. Department of Medical Pharmacology, Hacettepe University Faculty of Medicine, Ankara, Turkey

    Kubra Karadag, Bariscan Cimen, Mert Ertunc & Yildirim Sara

  2. Neuroscience and Neurotechnology Excellence Joint Application and Research Center (NÖROM), Ankara, Turkey

    Bariscan Cimen & Yildirim Sara

Authors
  1. Kubra Karadag
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  2. Bariscan Cimen
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  3. Mert Ertunc
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  4. Yildirim Sara
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Contributions

The draft of the letter was written by Kübra Karadağ and Barışcan Çimen. Mert Ertunç and Yıldırım Sara critically revised the letter for intellectual content.

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Correspondence to Kubra Karadag.

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Karadag, K., Cimen, B., Ertunc, M. et al. Does steroid increase LPS-induced sickness behaviors?. Neuropsychopharmacol. (2024). https://doi.org/10.1038/s41386-024-01838-x

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  • DOI: https://doi.org/10.1038/s41386-024-01838-x

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