This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Use of constitutive and inducible oncogene-containing iPSCs as surrogates for transgenic mice to study breast oncogenesis
Stem Cell Research & Therapy Open Access 27 May 2021
-
New insights into lineage restriction of mammary gland epithelium using parity-identified mammary epithelial cells
Breast Cancer Research Open Access 07 January 2014
Access options
Subscribe to this journal
Receive 50 print issues and online access
$259.00 per year
only $5.18 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Lo PK, Kanojia D, Liu X, Singh UP, Berger FG, Wang Q et al. CD49f and CD61 identify Her2/neu-induced mammary tumor-initiating cells that are potentially derived from luminal progenitors and maintained by the integrin-TGFβ signaling. Oncogene 2012; 31: 2614–2626.
Henry MD, Triplett AA, Oh KB, Smith GH, Wagner KU . Parity-induced mammary epithelial cells facilitate tumorigenesis in MMTV-neu transgenic mice. Oncogene 2004; 23: 6980–6985.
Matulka LA, Triplett AA, Wagner KU . Parity-induced mammary epithelial cells are multipotent and express cell surface markers associated with stem cells. Dev Biol 2007; 303: 29–44.
Boulanger CA, Wagner KU, Smith GH . Parity-induced mouse mammary epithelial cells are pluripotent, self-renewing and sensitive to TGF-beta1 expression. Oncogene 2005; 24: 552–560.
Booth BW, Boulanger CA, Anderson L, Smith GH . The mammary microenvironment restricts the tumorigenic phenotype of MMTV- neu-transformed tumor cells. Oncogene 2011; 30: 679–689.
Jeselsohn R, Brown NE, Arendt L, Klebba I, Hu MG, Kuperwasser C et al. Cyclin D1 kinase activity is required for the self- renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesis. Cancer Cell 2010; 17: 65–76.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Wagner, KU., Booth, B., Boulanger, C. et al. Multipotent PI-MECs are the true targets of MMTV-neu tumorigenesis. Oncogene 32, 1338 (2013). https://doi.org/10.1038/onc.2012.452
Published:
Issue Date:
DOI: https://doi.org/10.1038/onc.2012.452
This article is cited by
-
Use of constitutive and inducible oncogene-containing iPSCs as surrogates for transgenic mice to study breast oncogenesis
Stem Cell Research & Therapy (2021)
-
Amphiregulin regulates proliferation and migration of HER2-positive breast cancer cells
Cellular Oncology (2018)
-
The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis
Oncogene (2015)
-
Validation of an in vitro model of erbB2+ cancer cell redirection
In Vitro Cellular & Developmental Biology - Animal (2015)
-
New insights into lineage restriction of mammary gland epithelium using parity-identified mammary epithelial cells
Breast Cancer Research (2014)