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Kidney cancer

Carbonic anhydrase IX in resected clear cell RCC

Data from the ARISER trial indicate that carbonic anhydrase IX (CAIX) score predicts risk of recurrence and survival after curative nephrectomy in patients with localized high-risk clear cell renal carcinoma. Should CAIX staining be quantified to stratify risk after nephrectomy in all such patients?

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Acknowledgements

J.L. is supported by the National Institute for Health Research Royal Marsden Hospital/Institute of Cancer Research Biomedical Research Centre for Cancer.

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Correspondence to James Larkin.

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The authors declare no competing financial interests.

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Pickering, L., Larkin, J. Carbonic anhydrase IX in resected clear cell RCC. Nat Rev Urol 12, 309–310 (2015). https://doi.org/10.1038/nrurol.2015.124

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