Before 2009, no controlled trials of percutaneous tibial nerve stimulation (PTNS) for overactive bladder had been reported. However, publication of a randomized unblinded tolterodine-controlled trial of PTNS and the reporting of two blinded placebo-controlled studies now provide level 1b evidence of efficacy. PTNS should, therefore, be considered as a treatment option in this setting.
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V. Khullar declares he has served as a consultant for, and received honoraria and grant/research support from Astellas and Pfizer. He has served as a consultant and received grant/research support from Allergan and Novartis. R. Cartwright declares no competing interests.
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Cartwright, R., Khullar, V. Percutaneous tibial nerve stimulation for overactive bladder. Nat Rev Urol 7, 181–182 (2010). https://doi.org/10.1038/nrurol.2010.39
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DOI: https://doi.org/10.1038/nrurol.2010.39
