Aspirin has been shown to be as effective (P <0.001) and safe as low-molecular-weight heparin (dalteparin) for the extended prevention of venous thromboembolism after total hip arthroplasty (THA). In this study, all patients initially received dalteparin for 10 days following surgery and were then randomized to receive either aspirin (n = 386) or dalteparin (n = 400) for a further 28 days. Thus, aspirin might be a convenient and inexpensive alternative to low-molecular-weight heparin for extended thromboprophylaxis post-THA.
ORIGINAL RESEARCH PAPER
Anderson, D. R. et al. Aspirin versus low-molecular-weight heparin for extended venous thromboembolism prophylaxis after total hip arthroplasty: a randomized trial. Ann. Intern. Med. 158, 800–806 (2013)
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Aspirin an alternative for post-THA thromboprophylaxis. Nat Rev Rheumatol 9, 444 (2013). https://doi.org/10.1038/nrrheum.2013.97
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DOI: https://doi.org/10.1038/nrrheum.2013.97