In a meta-analysis of data from 7 studies and a total of 944 patients with osteoporosis, treatment with parathyroid hormone (PTH) was shown to provide significantly greater improvements in bone mineral density (BMD) at the spine and hip compared with bisphosphonate therapy. However, BMD at the distal radius improved to a greater extent following bisphosphonate therapy than with PTH treatment.
ORIGINAL RESEARCH PAPER
Shen, L. et al. Parathyroid hormone versus bisphosphonate treatment on bone mineral density in osteoporosis therapy: a meta-analysis of randomized controlled trials. PLoS ONE 6, e26267 (2011)
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Parathyroid hormone versus bisphonates: which provides greater BMD improvements in osteoporosis?. Nat Rev Rheumatol 7, 682 (2011). https://doi.org/10.1038/nrrheum.2011.180
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DOI: https://doi.org/10.1038/nrrheum.2011.180
