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End-stage renal disease

Dual transplantation—the immunological role of the liver

Kidney transplant recipients who also receive a partial liver allograft have better long-term outcomes than those who receive a kidney alone, despite the more-complex surgery. Understanding how the liver exerts these beneficial effects might enable their exploitation in the future.

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Acknowledgements

A.S.F.'s research group is supported by UK Medical Research Council and by the National Institute for Health Research Biomedical Research Centre based at Guy's and St Thomas' National Health Service Foundation Trust and King's College London.

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Correspondence to Alberto Sanchez-Fueyo.

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The authors declare no competing financial interests.

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Martinez-Llordella, M., Sanchez-Fueyo, A. Dual transplantation—the immunological role of the liver. Nat Rev Nephrol 10, 364–365 (2014). https://doi.org/10.1038/nrneph.2014.78

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