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Chronic kidney disease

Does serum phosphate predict death and ESRD in CKD patients?

Mehrotra and colleagues report that serum phosphate does not predict subsequent death or development of end-stage renal disease in a community-based cohort of people with chronic kidney disease (CKD). This finding conflicts with previous research and questions the relevance of serum phosphate level to outcomes in the context of CKD.

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Correspondence to David C. Wheeler.

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Competing interests

D. C. Wheeler declares associations with the following companies: Abbott (speakers' bureau, research/grant support), Amgen (consultant, speakers' bureau), Baxter (consultant), Fresenius (speakers' bureau), Genzyme (speakers' bureau, research/grant support), Otsuka (speakers' bureau), Shire (speakers' bureau), Vifor Pharma (speakers' bureau).

R. Haynes declares no competing interests.

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Haynes, R., Wheeler, D. Does serum phosphate predict death and ESRD in CKD patients?. Nat Rev Nephrol 9, 438–439 (2013). https://doi.org/10.1038/nrneph.2013.128

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