High-flux biocompatible synthetic dialyser membranes and ultrapure dialysate might improve the quality and effectiveness of haemodialysis. However, a recent randomized controlled trial showed no effect of membrane permeability or dialysate bacteriological quality on the incidence of fatal and nonfatal cardiovascular events in patients with end-stage renal disease undergoing haemodialysis.
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M. Grooteman has received research or grant support from Fresenius Medical Care, Gambro and Baxter. M. Nubé has received research or grant support from Fresenius Medical Care, Gambro and Baxter.
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Grooteman, M., Nubé, M. Membrane flux, dialysate purity and cardiovascular outcomes. Nat Rev Nephrol 9, 439–441 (2013). https://doi.org/10.1038/nrneph.2013.127
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DOI: https://doi.org/10.1038/nrneph.2013.127