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Dialysis

Membrane flux, dialysate purity and cardiovascular outcomes

High-flux biocompatible synthetic dialyser membranes and ultrapure dialysate might improve the quality and effectiveness of haemodialysis. However, a recent randomized controlled trial showed no effect of membrane permeability or dialysate bacteriological quality on the incidence of fatal and nonfatal cardiovascular events in patients with end-stage renal disease undergoing haemodialysis.

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Correspondence to Muriel Grooteman.

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Competing interests

M. Grooteman has received research or grant support from Fresenius Medical Care, Gambro and Baxter. M. Nubé has received research or grant support from Fresenius Medical Care, Gambro and Baxter.

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Grooteman, M., Nubé, M. Membrane flux, dialysate purity and cardiovascular outcomes. Nat Rev Nephrol 9, 439–441 (2013). https://doi.org/10.1038/nrneph.2013.127

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