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Prognostic value of blood pressure in patients on hemodialysis

Low pre-dialysis blood pressure is associated with an increased risk of mortality, but whether a high blood pressure level affects outcomes among patients on dialysis—as it does in the general population—is unclear. A recent study has found that higher systolic blood pressure measurements obtained outside the dialysis unit are associated with an increased risk of death, but that standard blood pressure recording in the dialysis unit has limited usefulness as a prognostic indicator.

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References

  1. Charra, B. et al. Survival as an index of adequacy of dialysis. Kidney Int. 41, 1286–1291 (1992).

    Article  CAS  Google Scholar 

  2. Foley, R. N. et al. Impact of hypertension on cardiomyopathy, morbidity and mortality in end-stage renal disease. Kidney Int. 49, 1379–1385 (1996).

    Article  CAS  Google Scholar 

  3. Port, F. K. et al. Predialysis blood pressure and mortality risk in a national sample of maintenance hemodialysis patients. Am. J. Kidney Dis. 33, 507–517 (1999).

    Article  CAS  Google Scholar 

  4. Zager, P. G. et al. “U” curve association of blood pressure and mortality in hemodialysis patients. Kidney Int. 54, 561–569 (1998).

    Article  CAS  Google Scholar 

  5. Stidley, C. A. et al. Changing relationship of blood pressure with mortality over time among hemodialysis patients. J. Am. Soc. Nephrol. 17, 513–520 (2006).

    Article  Google Scholar 

  6. Agarwal, R. Blood pressure and mortality among hemodialysis patients. Hypertension 55, 762–768 (2010).

    Article  CAS  Google Scholar 

  7. Agarwal, R., Peixoto, A. J., Santos, S. F. & Zoccali, C. Pre- and postdialysis blood pressures are imprecise estimates of interdialytic ambulatory blood pressure. Clin. J. Am. Soc. Nephrol. 1, 389–398 (2006).

    Article  Google Scholar 

  8. Zoccali, C. et al. Prediction of left ventricular geometry by clinic, pre-dialysis and 24-h ambulatory BP monitoring in hemodialysis patients: CREED investigators. J. Hypertens. 17, 1751–1758 (1999).

    Article  CAS  Google Scholar 

  9. Heerspink, H. J. et al. Effect of lowering blood pressure on cardiovascular events and mortality in patients on dialysis: a systematic review and meta-analysis of randomised controlled trials. Lancet 373, 1009–1015 (2009).

    Article  Google Scholar 

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Chazot, C. Prognostic value of blood pressure in patients on hemodialysis. Nat Rev Nephrol 6, 506–508 (2010). https://doi.org/10.1038/nrneph.2010.95

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