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Decade in review—hepatocellular carcinoma

HCC—subtypes, stratification and sorafenib

The past 10 years have represented a whirlwind of activity with regard to information on the risk factors, aetiopathogenesis, diagnosis and treatment of hepatocellular carcinoma. I will describe what I consider to be the major advances from both a tumour biology perspective and a clinical perspective over the past 10 years.

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Figure 1: Future strategies for HCC diagnosis and treatment.

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Acknowledgements

This work was supported by National Institute of Health Grant DK59427 and the Mayo Clinic.

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Correspondence to Gregory J. Gores.

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Gores, G. HCC—subtypes, stratification and sorafenib. Nat Rev Gastroenterol Hepatol 11, 645–647 (2014). https://doi.org/10.1038/nrgastro.2014.157

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