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Clinical guidelines

HFE hemochromatosis—screening, diagnosis and management

Nature Reviews Gastroenterology & Hepatology volume 7, pages 482–484 (2010)Cite this article

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Hemochromatosis associated with HFE C282Y homozygosity affects persons of western European descent, and is the most common and well-characterized primary iron overload disorder worldwide. New clinical practice guidelines summarize current knowledge of the prevalence and penetrance of C282Y homozygosity and provide evidence-based recommendations for diagnosis and management of patients with HFE hemochromatosis.

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References

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Authors and Affiliations

  1. Southern Iron Disorders Center, G105, 2022 Brookwood Medical Center Drive, Birmingham, 35209, AL, USA

    James C. Barton

  2. Division of Gastroenterology, Department of Medicine, London Health Sciences Center, London, ON N6A 2E8, Canada

    Paul C. Adams

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  1. James C. Barton
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  2. Paul C. Adams
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Correspondence to James C. Barton.

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Competing interests

J. C. Barton declares no competing interests. P. C. Adams declares consultancy and research support from Novartis.

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Barton, J., Adams, P. HFE hemochromatosis—screening, diagnosis and management. Nat Rev Gastroenterol Hepatol 7, 482–484 (2010). https://doi.org/10.1038/nrgastro.2010.132

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