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Obesity

Beige adipocytes—will they beat obesity?

Nature Reviews Endocrinology volume 11, pages 694–696 (2015)Cite this article

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The mechanistic link between the FTO locus and risk of obesity has remained elusive. However, a new study presents compelling evidence suggesting that the browning of white adipocytes into beige adipocytes (together with regulation of thermogenesis), might be an important and potentially modifiable pathway for development of obesity therapeutics.

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Figure 1: Therapeutic potentials arising from the FTO locus.

References

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  1. The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 1, Copenhagen, DK-2100, Denmark

    Camilla H. Sandholt & Oluf Pedersen

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  1. Camilla H. Sandholt
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  2. Oluf Pedersen
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Correspondence to Oluf Pedersen.

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The authors declare no competing financial interests.

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Sandholt, C., Pedersen, O. Beige adipocytes—will they beat obesity?. Nat Rev Endocrinol 11, 694–696 (2015). https://doi.org/10.1038/nrendo.2015.178

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