In an analysis of data from NHANES spanning from 1999 to 2010, Tuot et al. address two linked questions. Which patients with diabetes mellitus and renal insufficiency are reasonable candidates for metformin therapy and how does this treatment depend on the approach used to measure renal function?
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Z.B. has received honoraria from Astra Zeneca, Janssen, Merck and NovoNordisk. Z.B. has also received consulting fees from Amgen, Astra Zeneca, Janssen, Merck, NovoNordisk and Novartis. Z.B. also owns stock holdings in Baxter International, CVS Caremark, Novartis, Roche Holdings and St Jude Medical.
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Bloomgarden, Z. Metformin and renal insufficiency—is 45, or even 30, the new 60?. Nat Rev Endocrinol 11, 693–694 (2015). https://doi.org/10.1038/nrendo.2015.166
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DOI: https://doi.org/10.1038/nrendo.2015.166