A landmark article by The Cancer Genome Atlas Research network describes the genetic landscape of papillary thyroid carcinoma (PTC). This study identifies oncogenic driver lesions, highlights molecular pathways that drive cancer formation and defines clinically relevant disease subtypes. These findings have far-reaching implications with respect to molecular diagnosis and targeted therapies for PTC.
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This study was supported by the Italian Association for Cancer Research (AIRC).
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Santoro, M., Melillo, R. The genomic landscape of papillary thyroid carcinoma. Nat Rev Endocrinol 11, 133–134 (2015). https://doi.org/10.1038/nrendo.2014.209
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DOI: https://doi.org/10.1038/nrendo.2014.209
