Plasma levels of fluorescent oxidation products (FlOPs) measured at baseline in a group of 996 postmenopausal women from the Nurses' Health Study were positively associated with risk of hip fracture. This association was seen for FlOPs measured at 360 nm excitation and 420 nm emission wavelengths. The hazard ratios for hip fracture were 2.11 (95% CI 0.88–5.10) and 2.67 (95% CI 1.14–6.27) for women in the second and third tertiles of FIOP levels when compared with women in the first FlOP tertile.
References
Yang, S. et al. Association between global biomarkers of oxidative stress and hip fracture in postmenopausal women: a prospective study. J. Bone Miner. Res. 10.1002/jbmr.2302
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Markers of oxidative stress associated with risk of hip fracture in postmenopausal women. Nat Rev Endocrinol 10, 512 (2014). https://doi.org/10.1038/nrendo.2014.112
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DOI: https://doi.org/10.1038/nrendo.2014.112