Plasma levels of fluorescent oxidation products (FlOPs) measured at baseline in a group of 996 postmenopausal women from the Nurses' Health Study were positively associated with risk of hip fracture. This association was seen for FlOPs measured at 360 nm excitation and 420 nm emission wavelengths. The hazard ratios for hip fracture were 2.11 (95% CI 0.88–5.10) and 2.67 (95% CI 1.14–6.27) for women in the second and third tertiles of FIOP levels when compared with women in the first FlOP tertile.