According to a large epidemiologic study, a majority of American children are vitamin D insufficient or deficient. In addition to negative effects on bone metabolism, low vitamin D levels in the pediatric population are associated with adverse cardiovascular risk factors, including an increase in systolic blood pressure and a reduction in HDL cholesterol levels.
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DiMeglio, L. Vitamin D and cardiovascular disease risk in children. Nat Rev Endocrinol 6, 12–13 (2010). https://doi.org/10.1038/nrendo.2009.248
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DOI: https://doi.org/10.1038/nrendo.2009.248
