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Hypertension

Do calcium-channel blockers increase breast cancer risk?

A case–control study of five classes of antihypertensive medication used among 2,851 women shows that taking calcium-channel blockers for ≥10 years is associated with increased risk of invasive ductal and lobular breast carcinoma. These results are intriguing, but warrant additional investigation given the study limitations and inconsistent findings in the literature.

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Acknowledgements

The views expressed in this article are those of the authors and do not necessarily reflect the position or policy of Stanford University School of Medicine or Harvard Medical School.

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Correspondence to JoAnn E. Manson.

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Wang, A., Manson, J. Do calcium-channel blockers increase breast cancer risk?. Nat Rev Cardiol 10, 621–622 (2013). https://doi.org/10.1038/nrcardio.2013.155

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