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One cell's poison is another cell's cure

Nature Neuroscience volume 15, pages 505–506 (2012)Cite this article

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A drug that promotes cell death in cancer cells prevents cell death in post-ischemic neurons. These contrasting effects stem from the distinct actions of the anti-apoptotic protein Bcl-xL and its cleavage product, ΔN-Bcl-xL.

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Figure 1: Contrasting effects of ABT-737 in cancer cells and post-ischemic neurons.

Katie Vicari

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  1. and the Department of Neurology, Raymond A. Swanson is in the Neurology and Rehabilitation Service, San Francisco Veterans Affairs Medical Center, University of California, San Francisco, San Francisco, California, USA.,

    Raymond A Swanson

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  1. Raymond A Swanson
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Correspondence to Raymond A Swanson.

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Swanson, R. One cell's poison is another cell's cure. Nat Neurosci 15, 505–506 (2012). https://doi.org/10.1038/nn.3071

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