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Pathogenesis: Infections causing gastric cancer

Nature Microbiology volume 1, Article number: 16038 (2016) Cite this article

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A viral infection can reduce expression of a host phosphatase that would otherwise dampen the oncogenic activity of a bacterial virulence factor. The results suggest a possible mechanism for cooperation of infections in the development of stomach cancer.

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Figure 1: Model for EBV exacerbation of CagA-mediated oncogenic signalling.

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  1. Paul Farrell is in the Section of Virology, Imperial College Faculty of Medicine, Norfolk Place, London W2 1PG, UK.,

    Paul Farrell

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  1. Paul Farrell
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Correspondence to Paul Farrell.

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Farrell, P. Pathogenesis: Infections causing gastric cancer. Nat Microbiol 1, 16038 (2016). https://doi.org/10.1038/nmicrobiol.2016.38

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