Isobaric tagging methods allow multiplexed quantitative analysis of a wide variety of proteome samples but have been severely limited by problems of accuracy. Two groups now explore this issue and provide complementary solutions to address the problem.
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Christoforou, A., Lilley, K. Taming the isobaric tagging elephant in the room in quantitative proteomics. Nat Methods 8, 911–913 (2011). https://doi.org/10.1038/nmeth.1736
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DOI: https://doi.org/10.1038/nmeth.1736
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