The preclinical intersection of molecular imaging and gene- and cell-based therapies will enable more informed and effective clinical translation. We discuss how imaging can monitor cell and gene fate and function in vivo and overcome barriers associated with these therapies.
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Emerging Imaging Modalities in Regenerative Medicine
Current Pathobiology Reports Open Access 28 January 2015
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Acknowledgements
This work was supported in part by grants from NIH R01 HL093172, NIH R01 EB009689, NIH R01 HL095571, CIRM DR2-05394 and CIRM TR3-05556 (J.C.W).
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Kooreman, N., Ransohoff, J. & Wu, J. Tracking gene and cell fate for therapeutic gain. Nature Mater 13, 106–109 (2014). https://doi.org/10.1038/nmat3868
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DOI: https://doi.org/10.1038/nmat3868
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