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Acknowledgements
We thank G. Mazzeo for support. We are indebted to S. Filoni for his valuable guidance. We thank S. Dolci (Department of Biomedicine and Prevention, University of Rome “Tor Vergata”) for transgenic c-Kit mice, A.M. Lena (Department of Experimental Medicine and Biochemical Sciences, University of Rome “Tor Vergata”) for the SaosTAp63alfa cell line and F. Maina and C. Gargioli for suggestions. We acknowledge support from Associazione Italiana per la Ricerca sul Cancro to S.G. and G.C. Research in M.D.'s lab is supported by the “Recherche Cancer et Sang,” the “Recherches Scientifiques Luxembourg” association, the “Een Haerz fir kriibskrank Kanner” association, the Action Lions “Vaincre le Cancer” association and Televie Luxembourg.
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E.M. did mouse injections, immunohistochemistry, statistical analysis of data and ex vivo bleomycin experiments; C.D.B. helped with in vivo and ex vivo experiments; F.G.K. made ovary fragments and did TUNEL; S.M.C. and S.B. did follicle counting; S.C. did FACS analysis; F.M. did cell culturing; M.M. provided support for in vivo experiments; M.D.F. contributed to scientific discussions; M.D. provides support to complete this study; G.C. provided support and critical reading of the manuscript; S.G. designed the study, set up the immunohistochemistry-based approach, supervised the project and wrote the manuscript.
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Maiani, E., Di Bartolomeo, C., Klinger, F. et al. Reply to: Cisplatin-induced primordial follicle oocyte killing and loss of fertility are not prevented by imatinib. Nat Med 18, 1172–1174 (2012). https://doi.org/10.1038/nm.2852
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DOI: https://doi.org/10.1038/nm.2852
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