A unique guanosine-flanked Y-form DNA triggers innate cGAS-dependent responses that lead to upregulation of the production of type I interferons.
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Chiang, J., Gack, M. Reading the fine print: sequence-specific activation of cGAS. Nat Immunol 16, 1009–1010 (2015). https://doi.org/10.1038/ni.3274
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DOI: https://doi.org/10.1038/ni.3274