Adult T cell leukemia/lymphoma (ATL) is a neoplasm linked to human T-lymphotropic virus type-1 (HTLV-1) infection and is refractory to current combination chemotherapy. A large genomic and transcriptomic study of ATL now provides detailed insight into the molecular lesions implicated in the development of this T cell malignancy.
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Vicente, C., Cools, J. The genomic landscape of adult T cell leukemia/lymphoma. Nat Genet 47, 1226–1227 (2015). https://doi.org/10.1038/ng.3428
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DOI: https://doi.org/10.1038/ng.3428