Mycobacteria produce carbohydrates of exceptional structures that are covalently modified by unique substituents, whose functional characterization could expand our understanding of how mycobacteria adapt to their environment.
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Acknowledgements
We thank P.J. Brennan for critical reading of the manuscript. Studies on the chemical modifications of mycobacterial carbohydrates in the authors' laboratory were supported by the National Institute of Allergy and Infectious Diseases (NIAID) and the National Institutes of Health (NIH) grants AI064798 and AI116525. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.
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Angala, S., Palčeková, Z., Belardinelli, J. et al. Covalent modifications of polysaccharides in mycobacteria. Nat Chem Biol 14, 193–198 (2018). https://doi.org/10.1038/nchembio.2571
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DOI: https://doi.org/10.1038/nchembio.2571
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