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Complex molecular dynamics in the spotlight

Nature Biotechnology volume 28, pages 564–565 (2010)Cite this article

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Zero-mode waveguides illuminate the process of translation.

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Figure 1: Zero-mode waveguide (ZMW) technology reveals insights into the actions of single molecules and nanomachines.

References

  1. Weiss, S. Science 283, 1676–1683 (1999).

    Article  CAS  Google Scholar 

  2. Eid, J. et al. Science 323, 133–138 (2009).

    Article  CAS  Google Scholar 

  3. Uemura, S. et al. Nature 464, 1012–1017 (2010).

    Article  CAS  Google Scholar 

  4. Green, R. & Noller, H.F. Annu. Rev. Biochem. 66, 679–716 (1997).

    Article  CAS  Google Scholar 

  5. Levene, M.J. et al. Science 299, 682–686 (2003).

    Article  CAS  Google Scholar 

  6. Marshall, R.A., Aitken, C.E., Dorywalska, M. & Puglisi, J.D. Annu. Rev. Biochem. 77, 177–203 (2008).

    Article  CAS  Google Scholar 

  7. Fei, J., Kosuri, P., MacDougall, D.D. & Gonzalez, R.L. Mol. Cell 30, 348–359 (2008).

    Article  CAS  Google Scholar 

  8. Gesteland, R.F. & Atkins, J.F. Annu. Rev. Biochem. 65, 741–768 (1996).

    Article  CAS  Google Scholar 

  9. Zaher, H.S. & Green, R. Cell 136, 746–762 (2009).

    Article  CAS  Google Scholar 

  10. Xu, H., Zhu, P., Craighead, H.G. & Webb, W.W. Opt. Commun. 282, 1467–1471 (2009).

    Article  CAS  Google Scholar 

  11. Betzig, E. et al. Biophys. J. 49, 269–279 (1986).

    Article  CAS  Google Scholar 

  12. Lippincott-Schwartz, J. & Patterson, G.H. Trends Cell Biol. 19, 555–565 (2009).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Lois Pollack and Watt W. Webb are in the School of Applied and Engineering Physics, Cornell University, Ithaca, New York, USA.,

    Lois Pollack & Watt W Webb

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  1. Lois Pollack
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  2. Watt W Webb
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Correspondence to Watt W Webb.

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Competing interests

W.W.W. is on the scientific advisory board of and holds stock in Pacific Biosciences, which is developing a DNA-sequencing machine. He is also a co-inventor of the patented technology on which the machine is based, including the sequencing methodology and the zero-mode waveguide methodology.

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Pollack, L., Webb, W. Complex molecular dynamics in the spotlight. Nat Biotechnol 28, 564–565 (2010). https://doi.org/10.1038/nbt0610-564

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