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A microbial factory for diverse chemicals

An array of functionalized small molecules is efficiently synthesized in bacteria.

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Figure 1: Cheong et al.1 generate a large array of functionalized small molecules by feeding the reverse β-oxidation cycle with primer and extender molecules that contain diverse functional groups (R1 and R2) and using different termination pathways.

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Correspondence to Costas D Maranas.

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Ng, C., Chowdhury, A. & Maranas, C. A microbial factory for diverse chemicals. Nat Biotechnol 34, 513–515 (2016). https://doi.org/10.1038/nbt.3565

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