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Cancer

Killing from the inside

Nature volume 502, pages 312–313 (2013)Cite this article

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Lysosomes are the main degradative compartment in cells, but they are also involved in cell-death pathways. Studies using existing drugs show that lysosomes are excellent pharmacological targets for selectively destroying cancer cells.

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Figure 1: Lysosomes as a therapeutic cancer target.

Notes

  1. *This News & Views article was published online on 2 October 2013.

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Author information

Authors and Affiliations

  1. Paul Saftig is at the Biochemisches Institut, Christian Albrechts-Universität Kiel, 24118 Kiel, Germany.,

    Paul Saftig

  2. Konrad Sandhoff is at the Life and Medical Sciences Institute, Universität Bonn, 53121 Bonn, Germany.,

    Konrad Sandhoff

Authors
  1. Paul Saftig
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  2. Konrad Sandhoff
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Correspondence to Paul Saftig.

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Saftig, P., Sandhoff, K. Killing from the inside. Nature 502, 312–313 (2013). https://doi.org/10.1038/nature12692

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